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11/8/23 TRF Requested Updates

11/8/23 TRF Requested Updates

Owned by Gretl Glick
Nov 14, 2023

 

SUBMITTER INFORMATION (no changes)

 

PATIENT INFORMATION (no changes)

 

SPECIMEN INFORMATION (need changes)

 

 

 

 

Modifications:

  1. Move “Sediment-AFB Negative” from “Other” to “Sediment”

a.      if “Sediment-AFB Negative” selected:

                                                    i.     show selection “*Material approved by CDPH”: Yes/No

AND

                                                   ii.     display message:

 

  1. Under “Other” add additional options:

a.      Processed tissue

b.      Mixed culture

c.      Non-viable culture

d.      Other (add comment field, if selected)

  1. Rename “Other” to “Other (e.g. tissue, mixed culture)”

 

 

 

TEST REQUESTED

Sequencing-Based DST (performed by default)

Please see detailed testing algorithm on test information webpage.

 

Phenotypic DST (pDST)

 

pDST is recommended to be performed in conjunction with sequencing-based DST, unless pDST has already been performed or will be conducted elsewhere. Please choose a pDST test below (leave blank if not needed):

 

Additional test option:

 

 First-line pDST (RIF, INH, PZA[KV1] , EMB)

 

Additional test option:

 

Second-line pDST (MOX, AMK, CAP, ETA, KAN, RFB)                                                                              

 

Additional test option:

 

First-line pDST [KV2] for 4-month RPT-MOX regimen (RIF, INH, PZA, MOX)[KV3] 

 

 

WGS Genotyping

 

WGS Genotyping is performed by default on culture submissions or isolates obtained from submitted sediments and data will be submitted to the CDC for analysis/National Surveillance.

 

*Please confirm that you would like TB DST Reference Center to perform WGS Genotyping:

  • Yes, please perform default testing

  • No, submitter will be responsible for submitting necessary isolate and/or data  elsewhere

 

Has sequencing-based DST been performed by CDPH or CDC on a sample from this patient previously?

 

Yes No

 

 

 

SUBMITTING LABORATORY’S RESULTS

 

*Has MTBC been identified in the submitted specimen?

Yes    No

 

*Has any Rifampin resistance (RIF-R) been detected previously in the submitted specimen by molecular or growth-based testing?

Not Tested Not Detected Indeterminate Detected [KV8] 

 

*Has first-line DST been previously performed?

 

Yes No

 

Please select any that apply:

Drug resistant TB has been previously detected in this patient

Patient is not responding to treatment or was previously treated for TB

Mixed culture

Non-viable culture

Phenotypic DST failed due to low growth

 

 

Comments on Submitting Laboratory’s Results

 

SHIPPING (no changes)

GENERAL COMMENTS

Provide any additional information pertaining to the test requisition here

 

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