May 2024 TRF Requested Updates

 

SUBMITTER INFORMATION (no changes)

 

PATIENT INFORMATION (no changes)

 

SPECIMEN INFORMATION (need changes)

 

 

Modifications:

Modify the text below the “Sequencing-based DST” test option to state: “Whole Genome Sequencing (WGS) DST or targeted Next Generation Sequencing (tNGS) DST will be performed based on the type of submitted material. Please see detailed testing algorithm on test information webpage” The hyperlink is the same as was used in this message before.

 

SeqDST statement.png

 

 

 

TEST REQUESTED

 

 

Phenotypic DST (pDST) Section

On the LWP under Phenotypic DST (pDST) change the text of the following test orders:

• First-line pDST (RIF, INH, PZA, EMB) change to “First-line pDST (RIF, INH, EMB)” In small gray font below the box with selection include the text “pDST for PZA is performed on reflex based on WGS results

” • First-line pDST for 4-month RPT-MOX regimen (RIF, INH, PZA, MOX) change to “First-line pDST for 4-month RPT-MOX regimen (RIF, INH, MOX)” In small gray font below the box with selection include the text “pDST for PZA is performed on reflex based on WGS results”

 

 

LWP PZA Update.png

1. Change Section Title to “Test(s) Requested”.
Note:
2 .The colon after Requested and “Sequencing-Based DST (performed by default)” are to be removed.

  1. Under Test Requested Section. List the applicable test that are ordered in the following order with the following text (all in Bold):
    • Sequencing-Based DST
    • First-line pDST (RIF, INH, EMB)
    • Second-line pDST (MOX, AMK, CAP, ETA, KAN, RFB)
    • First-line pDST for 4-month RPT-MOX regimen (RIF, INH, MOX)
    • WGS Genotyping

4.Note:
Currently the order for WGS Genotyping is in the form of a statement/answer.
“TB DST Reference Center to perform WGS Genotyping:
Yes, please perform default testing”

We want to simplify to the above with just WGS Genotyping

 

 

 

 

 

 

SUBMITTING LABORATORY’S RESULTS

 

 

 

SHIPPING (no changes)

GENERAL COMMENTS

Provide any additional information pertaining to the test requisition here

 

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