2025-01-13 LIDR Meeting Notes

Hung Luu

Children’s

Riki Merrick

Vernetzt, APHL

Andrea Pitkus

UW

Pam Banning

3M - Solventum

Xavier Gansel

Biomerieux

Amy McCormick

Epic

Dan Rutz

Epic

Rob Rae

CAP

Rob Hausam

Hausam Consulting

Sandy Jones

CDC

Stan Huff

Graphite

Ed Heierman

Abbott / IICC

Andrew Quinn

Laurent Lardin

Biomerieux

Anthony Killeen

UMN

Craig Collom

Marti Velezis

 Sonrisa / FDA

Walter Sujansky

FDA

Susan Downer

JMC

Ralf Herzog

Roche

Cornelia Felder

Roche

Daniel Golson

JMC

Andrea Prada

JMC

Maria Sagat

CAP

Raja Cholan

FDA

Russ Ott

FDA

Akila Namasivayam

FDA

Desiree Mustaquim

CDC

Carmen Pugh

CDC

Christina Gallegos

APHL

John Spinosa

Lantana

Matthew Dietz

FDA

Victoria Derbyshire

FDA

Topic

Notes

Reviewing the comments on the LIDR White Paper = LIDR White Paper

Discussion:

2 new additions under problem #3

Open To Dos:

• Update reference style to use the numbers with reference Section (Riki has that prepped)

• Still need to check for best place to talk about CLSI AUTO-16/IHE LAW (question: has anyone implemented in the US in production?)

Review examples of merged cell LIVD file entries

https://aphlinformatics.atlassian.net/wiki/download/attachments/1938718763/Copy-HIV-Diagnostic-LOINC-Map_v5.xlsx?api=v2

essentially the repeating cells were merged for readability, they all would be separate LIVD file entries with the same UDI - think of the excel as a viewing tool (but currently also it needs to be the source of truth)

if you had LOINCs specific to Ser, that would be a separate LIDR entry,

LOINC for Ser or Pl are mapped to acellular blood SCT (can/should add SCT for that)

From LIDR perspective, every difference in a column produces a different LIDR entry (though not all of those would result in different mappings)

not all elements in LIDR will be needed for mapping (and some should probably be usable to exclude from mapping for labs (entries that are speicifc ONLY for at-home tests for example)

HIV file has 4 extra columns more that LIVD spec - those were requested by the CDC Epi folks:

• Assay Intent

• CLIA Complexity

• LOINC Used to Represent Other Tests

• Testkit Name

For the SARS-COV-2 file APHL also has a file with additional columns, that CDC ReportStream is using for their data analysis / conversion to HL7 ELR from csv file - a few examples:

• Non-prescription Testing

• Prescription Home Testing

• Over the Counter (OTC) Home Testing

• Telehealth Proctor Supervised

For the Reportable Conditions LIVD google sheet for crowdsourcing file we added some columns that would translate what is currently in the LIVD file to more detialed representations - example:

Vendor Comments → Clinical Context needed for mapping; USe case Glucose Challenge testing

the vendor provided LIVD file would indicate that the test can be used for Challenge testing, while in LIDR we would create separate entries with the respective proper CLinical Context for the different protocols that are available:

• ACOG

• AMA (Diabetes guidelines)

• gestational diabetes specific

• WHO

Reviewing minutes from the last call - Action Item Follow up

• Pull out the definitions from LIVD for test kit and equipment and put here: SHIELD Glossary

  • Review operational definition of “equivalence”

• Outreach to Dr. DeBaca

  • Hung will check for more info and maybe see, if she could participate in SHIELD

• Keep updating the googlesheet: Potassium LIVD data

• Shared Reportable Conditions LIVD google sheet for crowdsourcing with CSTE - added sign up sheet for PHAs to specific conditions and see how that develops

• Have LIVD File Repository Requirements

  Have draft budget (for setting up a web-based database and yearly maintenance): https://aphlinformatics.atlassian.net/wiki/download/attachments/915407143/LIDR - Budget.xlsx?api=v2

• Define next steps to migrate existing LIVD files into FHIR LIVD catalog format and find a FHIR server to host

• Marti can share the LIDR categorical data to instance data mapping for each element - DATE?

Next call

????

Adjourned

9: AM ET